Therapy development based on a chip model for inner ear disease
In 2023, Animalfree Research supported the development and validation of the first microtechnical chip model based on human cells that mimics the inner ear blood-labyrinth barrier in combination with Meniere’s disease. The funded in vitro model allows the inflammatory processes associated with the disease to be investigated and therapeutic options to be developed. At the same time, the animal-free model represents a milestone in the field of inner ear research.
Publication
Sekulic, M. et al. (2024) Neutrophil Extracellular Traps Affect Human Inner Ear Vascular Permeability. Int. J. Mol. Sci. 2024, 25, 9766.