A serum-free culture system for human primary ocular cells for research, drug development & production Blindness as a result of severe visual impairment caused by eye diseases affects the quality of life of over 40 million people worldwide. Gene and stem cell...
A dynamic cartilage-on-chip system to identify molecular mechanisms and new drug inhibitors of cartilage calcification in osteoarthritis Osteoarthritis is a degenerative joint disease in which inflammation occurs in joints. Knees, hips and hands are frequently...
New ways to use in vitro data as an alternative to animal testing for risk assessment and compatibility testing of substances. For the toxicological assessment of new chemicals and nanomaterials, 13,000 animals are still used today in Switzerland alone, depending on...
Neuronal cultures as a non-animal replacement method for the study of neuropathic pain and nerve cell diseases. Neuropathic pain occurs when peripheral nerves stop functioning properly, resulting in pain in the hands, feet, arms, legs, and trunk. There are many causes...
Establishment of a 3D bone metastasis model for patient-adapted analysis of therapy response. In advanced stages, many tumors settle primarily in the bones (prostate, breast carcinoma). This results in the need to develop innovative treatment concepts that prevent...
3R principles in wildlife research Animalfree Research supports the maintenance of the first online database on non-invasive or non-lethal methods and corresponding scientific studies in wildlife research, which is specifically aimed at wildlife biologists, ecologists...