{"id":2344,"date":"2023-04-03T14:36:56","date_gmt":"2023-04-03T12:36:56","guid":{"rendered":"https:\/\/2023-neu.animalfree-research.org\/en\/?p=2344"},"modified":"2023-04-08T14:30:16","modified_gmt":"2023-04-08T12:30:16","slug":"neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases","status":"publish","type":"post","link":"https:\/\/animalfree-research.org\/en\/blog\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\/","title":{"rendered":"Neuronal cultures as a non-animal replacement method for the study of neuropathic pain and nerve cell diseases."},"content":{"rendered":"<p>[et_pb_section fb_built=&#187;1&#8243; _builder_version=&#187;4.19.4&#8243; _module_preset=&#187;default&#187; global_colors_info=&#187;{}&#187;][et_pb_row _builder_version=&#187;4.19.4&#8243; _module_preset=&#187;default&#187; global_colors_info=&#187;{}&#187;][et_pb_column type=&#187;4_4&#8243; _builder_version=&#187;4.19.4&#8243; _module_preset=&#187;default&#187; global_colors_info=&#187;{}&#187;][et_pb_text admin_label=&#187;Titel&#187; _builder_version=&#187;4.20.2&#8243; _module_preset=&#187;default&#187; global_colors_info=&#187;{}&#187;]<\/p>\n<h1>Neuronal cultures as a non-animal replacement method for the study of neuropathic pain and nerve cell diseases.<\/h1>\n<p>[\/et_pb_text][et_pb_text admin_label=&#187;Lead&#187; _builder_version=&#187;4.20.2&#8243; _module_preset=&#187;default&#187; hover_enabled=&#187;0&#8243; global_colors_info=&#187;{}&#187; sticky_enabled=&#187;0&#8243;]<\/p>\n<div class=\"wp-block-columns has-2-columns\">\n<div class=\"wp-block-column\">\n<div class=\"wp-block-columns has-2-columns\">\n<div class=\"wp-block-column\">\n<div class=\"wp-block-columns has-2-columns\">\n<div class=\"wp-block-column\">\n<p><strong>Neuropathic pain occurs when peripheral nerves stop functioning properly, resulting in pain in the hands, feet, arms, legs, and trunk. There are many causes such as diabetes mellitus, alcoholism, infectious diseases, toxic effects or hereditary diseases.<\/strong><\/p>\n<p>The disease is common, with 20% of the population experiencing it once in a lifetime (lifetime prevalence = 20%). Pain research is a large field of research in neuroscience, in which tens of thousands of laboratory animals suffer and are killed in particularly stressful experiments.<\/p>\n<p>We are supporting a project to develop a cell model of the peripheral nervous system. The model is based on sensitive and motor neurons in co-culture with Schwann cells (= sheath and support cells of nerve processes) established from human cells. The model will allow for studying damage, symptoms and regeneration mechanisms of the peripheral nervous system mechanistically as well as electrophysiologically without animal experiments.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Neuropathic pain occurs when peripheral nerves stop functioning properly, resulting in pain in the hands, feet, arms, legs, and trunk. There are many causes such as diabetes mellitus, alcoholism, infectious diseases, toxic effects or hereditary diseases.<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[13],"tags":[],"class_list":["post-2344","post","type-post","status-publish","format-standard","hentry","category-current-projects"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Neuronal cultures as a non-animal replacement method for the study of neuropathic pain and nerve cell diseases. - Animalfree Research<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/animalfree-research.org\/en\/blog\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Neuronal cultures as a non-animal replacement method for the study of neuropathic pain and nerve cell diseases. - Animalfree Research\" \/>\n<meta property=\"og:description\" content=\"Neuropathic pain occurs when peripheral nerves stop functioning properly, resulting in pain in the hands, feet, arms, legs, and trunk. There are many causes such as diabetes mellitus, alcoholism, infectious diseases, toxic effects or hereditary diseases.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/animalfree-research.org\/en\/blog\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\/\" \/>\n<meta property=\"og:site_name\" content=\"Animalfree Research\" \/>\n<meta property=\"article:published_time\" content=\"2023-04-03T12:36:56+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-04-08T12:30:16+00:00\" \/>\n<meta name=\"author\" content=\"salu4anifre\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Geschrieben von\" \/>\n\t<meta name=\"twitter:data1\" content=\"salu4anifre\" \/>\n\t<meta name=\"twitter:label2\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data2\" content=\"2\u00a0Minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/animalfree-research.org\\\/en\\\/blog\\\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/animalfree-research.org\\\/en\\\/blog\\\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\\\/\"},\"author\":{\"name\":\"salu4anifre\",\"@id\":\"https:\\\/\\\/animalfree-research.org\\\/en\\\/#\\\/schema\\\/person\\\/ee0e0ae76af397af306b94894d1cabfb\"},\"headline\":\"Neuronal cultures as a non-animal replacement method for the study of neuropathic pain and nerve cell diseases.\",\"datePublished\":\"2023-04-03T12:36:56+00:00\",\"dateModified\":\"2023-04-08T12:30:16+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/animalfree-research.org\\\/en\\\/blog\\\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\\\/\"},\"wordCount\":259,\"commentCount\":0,\"articleSection\":[\"Current projects\"],\"inLanguage\":\"de-CH\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/animalfree-research.org\\\/en\\\/blog\\\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\\\/\",\"url\":\"https:\\\/\\\/animalfree-research.org\\\/en\\\/blog\\\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\\\/\",\"name\":\"Neuronal cultures as a non-animal replacement method for the study of neuropathic pain and nerve cell diseases. - Animalfree Research\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/animalfree-research.org\\\/en\\\/#website\"},\"datePublished\":\"2023-04-03T12:36:56+00:00\",\"dateModified\":\"2023-04-08T12:30:16+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/animalfree-research.org\\\/en\\\/#\\\/schema\\\/person\\\/ee0e0ae76af397af306b94894d1cabfb\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/animalfree-research.org\\\/en\\\/blog\\\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\\\/#breadcrumb\"},\"inLanguage\":\"de-CH\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/animalfree-research.org\\\/en\\\/blog\\\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/animalfree-research.org\\\/en\\\/blog\\\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/animalfree-research.org\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Neuronal cultures as a non-animal replacement method for the study of neuropathic pain and nerve cell diseases.\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/animalfree-research.org\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/animalfree-research.org\\\/en\\\/\",\"name\":\"Animalfree Research\",\"description\":\"Wir ersetzen Tierversuche.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/animalfree-research.org\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"de-CH\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/animalfree-research.org\\\/en\\\/#\\\/schema\\\/person\\\/ee0e0ae76af397af306b94894d1cabfb\",\"name\":\"salu4anifre\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"de-CH\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/8e7ee078655c36b9d4d931e9b33cf2ad1127d28bbdd700b721cc4bc15514cf06?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/8e7ee078655c36b9d4d931e9b33cf2ad1127d28bbdd700b721cc4bc15514cf06?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/8e7ee078655c36b9d4d931e9b33cf2ad1127d28bbdd700b721cc4bc15514cf06?s=96&d=mm&r=g\",\"caption\":\"salu4anifre\"},\"url\":\"https:\\\/\\\/animalfree-research.org\\\/en\\\/blog\\\/author\\\/salu4anifre\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Neuronal cultures as a non-animal replacement method for the study of neuropathic pain and nerve cell diseases. - Animalfree Research","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/animalfree-research.org\/en\/blog\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\/","og_locale":"de_DE","og_type":"article","og_title":"Neuronal cultures as a non-animal replacement method for the study of neuropathic pain and nerve cell diseases. - Animalfree Research","og_description":"Neuropathic pain occurs when peripheral nerves stop functioning properly, resulting in pain in the hands, feet, arms, legs, and trunk. There are many causes such as diabetes mellitus, alcoholism, infectious diseases, toxic effects or hereditary diseases.","og_url":"https:\/\/animalfree-research.org\/en\/blog\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\/","og_site_name":"Animalfree Research","article_published_time":"2023-04-03T12:36:56+00:00","article_modified_time":"2023-04-08T12:30:16+00:00","author":"salu4anifre","twitter_card":"summary_large_image","twitter_misc":{"Geschrieben von":"salu4anifre","Gesch\u00e4tzte Lesezeit":"2\u00a0Minuten"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/animalfree-research.org\/en\/blog\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\/#article","isPartOf":{"@id":"https:\/\/animalfree-research.org\/en\/blog\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\/"},"author":{"name":"salu4anifre","@id":"https:\/\/animalfree-research.org\/en\/#\/schema\/person\/ee0e0ae76af397af306b94894d1cabfb"},"headline":"Neuronal cultures as a non-animal replacement method for the study of neuropathic pain and nerve cell diseases.","datePublished":"2023-04-03T12:36:56+00:00","dateModified":"2023-04-08T12:30:16+00:00","mainEntityOfPage":{"@id":"https:\/\/animalfree-research.org\/en\/blog\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\/"},"wordCount":259,"commentCount":0,"articleSection":["Current projects"],"inLanguage":"de-CH"},{"@type":"WebPage","@id":"https:\/\/animalfree-research.org\/en\/blog\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\/","url":"https:\/\/animalfree-research.org\/en\/blog\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\/","name":"Neuronal cultures as a non-animal replacement method for the study of neuropathic pain and nerve cell diseases. - Animalfree Research","isPartOf":{"@id":"https:\/\/animalfree-research.org\/en\/#website"},"datePublished":"2023-04-03T12:36:56+00:00","dateModified":"2023-04-08T12:30:16+00:00","author":{"@id":"https:\/\/animalfree-research.org\/en\/#\/schema\/person\/ee0e0ae76af397af306b94894d1cabfb"},"breadcrumb":{"@id":"https:\/\/animalfree-research.org\/en\/blog\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\/#breadcrumb"},"inLanguage":"de-CH","potentialAction":[{"@type":"ReadAction","target":["https:\/\/animalfree-research.org\/en\/blog\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/animalfree-research.org\/en\/blog\/neuronal-cultures-as-a-non-animal-replacement-method-for-the-study-of-neuropathic-pain-and-nerve-cell-diseases\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/animalfree-research.org\/en\/"},{"@type":"ListItem","position":2,"name":"Neuronal cultures as a non-animal replacement method for the study of neuropathic pain and nerve cell diseases."}]},{"@type":"WebSite","@id":"https:\/\/animalfree-research.org\/en\/#website","url":"https:\/\/animalfree-research.org\/en\/","name":"Animalfree Research","description":"Wir ersetzen Tierversuche.","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/animalfree-research.org\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"de-CH"},{"@type":"Person","@id":"https:\/\/animalfree-research.org\/en\/#\/schema\/person\/ee0e0ae76af397af306b94894d1cabfb","name":"salu4anifre","image":{"@type":"ImageObject","inLanguage":"de-CH","@id":"https:\/\/secure.gravatar.com\/avatar\/8e7ee078655c36b9d4d931e9b33cf2ad1127d28bbdd700b721cc4bc15514cf06?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/8e7ee078655c36b9d4d931e9b33cf2ad1127d28bbdd700b721cc4bc15514cf06?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/8e7ee078655c36b9d4d931e9b33cf2ad1127d28bbdd700b721cc4bc15514cf06?s=96&d=mm&r=g","caption":"salu4anifre"},"url":"https:\/\/animalfree-research.org\/en\/blog\/author\/salu4anifre\/"}]}},"_links":{"self":[{"href":"https:\/\/animalfree-research.org\/en\/wp-json\/wp\/v2\/posts\/2344","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/animalfree-research.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/animalfree-research.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/animalfree-research.org\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/animalfree-research.org\/en\/wp-json\/wp\/v2\/comments?post=2344"}],"version-history":[{"count":4,"href":"https:\/\/animalfree-research.org\/en\/wp-json\/wp\/v2\/posts\/2344\/revisions"}],"predecessor-version":[{"id":2369,"href":"https:\/\/animalfree-research.org\/en\/wp-json\/wp\/v2\/posts\/2344\/revisions\/2369"}],"wp:attachment":[{"href":"https:\/\/animalfree-research.org\/en\/wp-json\/wp\/v2\/media?parent=2344"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/animalfree-research.org\/en\/wp-json\/wp\/v2\/categories?post=2344"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/animalfree-research.org\/en\/wp-json\/wp\/v2\/tags?post=2344"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}