{"id":2339,"date":"2023-04-03T14:35:30","date_gmt":"2023-04-03T12:35:30","guid":{"rendered":"https:\/\/2023-neu.animalfree-research.org\/en\/?p=2339"},"modified":"2025-08-27T08:48:05","modified_gmt":"2025-08-27T06:48:05","slug":"therapy-development-based-on-a-chip-model-for-inner-ear-disease","status":"publish","type":"post","link":"https:\/\/animalfree-research.org\/en\/blog\/therapy-development-based-on-a-chip-model-for-inner-ear-disease\/","title":{"rendered":"Therapy development based on a chip model for inner ear disease."},"content":{"rendered":"<p>[et_pb_section fb_built=&#187;1&#8243; _builder_version=&#187;4.19.4&#8243; _module_preset=&#187;default&#187; global_colors_info=&#187;{}&#187;][et_pb_row _builder_version=&#187;4.19.4&#8243; _module_preset=&#187;default&#187; global_colors_info=&#187;{}&#187;][et_pb_column type=&#187;4_4&#8243; _builder_version=&#187;4.19.4&#8243; _module_preset=&#187;default&#187; global_colors_info=&#187;{}&#187;][et_pb_text admin_label=&#187;Titel&#187; _builder_version=&#187;4.21.0&#8243; _module_preset=&#187;default&#187; hover_enabled=&#187;0&#8243; global_colors_info=&#187;{}&#187; sticky_enabled=&#187;0&#8243;]<\/p>\n<h1>Therapy development based on a chip model for inner ear disease<\/h1>\n<p>[\/et_pb_text][et_pb_text admin_label=&#187;Lead&#187; _builder_version=&#187;4.21.0&#8243; _module_preset=&#187;default&#187; hover_enabled=&#187;0&#8243; global_colors_info=&#187;{}&#187; sticky_enabled=&#187;0&#8243;]<\/p>\n<div class=\"wp-block-columns has-2-columns\">\n<p>In 2023, Animalfree Research supported the development and validation of the first microtechnical chip model based on human cells that mimics the inner ear blood-labyrinth barrier in combination with Meniere&#8217;s disease. The funded in vitro model allows the inflammatory processes associated with the disease to be investigated and therapeutic options to be developed. At the same time, the animal-free model represents a milestone in the field of inner ear research.\u200b<\/p>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=&#187;Publikationen&#187; _builder_version=&#187;4.19.4&#8243; _module_preset=&#187;default&#187; background_color=&#187;#2A6556&#8243; custom_margin=&#187;||||false|false&#187; custom_padding=&#187;|30px||30px|false|true&#187; border_radii=&#187;on|30px|30px|30px|30px&#187; global_colors_info=&#187;{}&#187; theme_builder_area=&#187;post_content&#187;][et_pb_column type=&#187;4_4&#8243; _builder_version=&#187;4.19.4&#8243; _module_preset=&#187;default&#187; global_colors_info=&#187;{}&#187; theme_builder_area=&#187;post_content&#187;][et_pb_text _builder_version=&#187;4.21.0&#8243; _module_preset=&#187;default&#187; text_text_color=&#187;#FFFFFF&#187; header_text_align=&#187;left&#187; header_text_color=&#187;#FFFFFF&#187; header_font_size=&#187;68px&#187; header_letter_spacing=&#187;-1px&#187; header_line_height=&#187;1.2em&#187; header_2_text_color=&#187;#FFFFFF&#187; header_2_line_height=&#187;1.6em&#187; header_3_font=&#187;|600|||||||&#187; header_3_text_color=&#187;#B3C965&#8243; custom_margin=&#187;0px||6px||false|false&#187; custom_padding=&#187;0px||0px||false|false&#187; hover_enabled=&#187;0&#8243; header_font_size_tablet=&#187;68px&#187; header_font_size_phone=&#187;34px&#187; header_font_size_last_edited=&#187;on|phone&#187; global_colors_info=&#187;{}&#187; theme_builder_area=&#187;post_content&#187; sticky_enabled=&#187;0&#8243;]<\/p>\n<h2>Publication<\/h2>\n<p>Sekulic, M. et al. (2024)\u00a0<a href=\"https:\/\/www.mdpi.com\/1422-0067\/25\/18\/9766\"><u>Neutrophil Extracellular Traps Affect<\/u><u>\u00a0<\/u><u>Human Inner Ear Vascular Permeability<\/u><\/a>.\u00a0Int. J. Mol. Sci. 2024, 25, 9766.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In 2023, Animalfree Research supported the development and validation of the first microtechnical chip model based on human cells that mimics the inner ear blood-labyrinth barrier in combination with Meniere&#8217;s disease.<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[11],"tags":[],"class_list":["post-2339","post","type-post","status-publish","format-standard","hentry","category-completed-projects"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Therapy development based on a chip model for inner ear disease. - Animalfree Research<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/animalfree-research.org\/en\/blog\/therapy-development-based-on-a-chip-model-for-inner-ear-disease\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Therapy development based on a chip model for inner ear disease. - 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